Scientist - Discovery - Bioanalytical

  • Charles River Laboratories
  • Mattawan, MI, USA
  • May 28, 2021

Job Description

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary We are seeking an Scientist for our Bioanalytical Team located in Mattawan, MI. The Scientist in Drug Metabolism Pharmacokinetics (DMPK) is responsible for developing and/or validating methods and/or procedures, to either quantify/synthesize chemical entities, or prepare formulated test articles or supporting compounds, or conduct studies of chemical compounds in vitro or in vivo, according to applicable Standard Operating Procedures (SOPs), study protocols and/or GxP regulations. Individuals in this role demonstrate expertise in their field, lead others through scientific mentorship and/or publications, complete assigned projects on time, and communicate effectively. A Scientist is expected to work independently, participate in process improvement initiatives, may supervise others, and may function as a Principal Investigator, Contributing Scientist, and/ or Study Director. The following are the minimum requirements related to the Scientist position. HS/GED/Associate degree and 15 or more years of relevant experience; or Bachelor’s/Master’s degree in a relevant field and 7-10 years of relevant experience; or Doctoral degree in a relevant field and 2-5 years of relevant experience. Experience in large molecule LC-MS/MS bioanalysis method development workflows (protein, peptide, oligonucleotides) is strongly preferred. Use of Sciex triple-quadrupole LC-MS/MS systems is preferred. Previous experience in a regulated GxP laboratory is preferred. Proficient using laboratory software applications (i.e., LIMS and data acquisition software). Working knowledge of GxPs and industry guidance documents. Ability to work extended hours beyond normal work schedule to include, but not limited to, evenings, weekends, extended shifts and/or extra shifts, sometimes on short notice. Familiarity with Microsoft Office Suite. Ability to work under specific time constraints. About Safety Assessment Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.